Research shows amygdala and insula retraining significantly reduces long COVID fatigue

Patients using the online AIR program experienced almost twice as much improvement in energy levels and demonstrated a fourfold increase in effectiveness in reducing fatigue when compared to the wellness program. The AIR intervention employed neuroplasticity techniques designed to create new neural pathways and retrain the amygdala and insula so the immune and autonomic nervous systems can return to homeostasis.
The study’s results on the effectiveness of AIR are consistent with previous research demonstrating its effectiveness in alleviating symptoms of other chronic conditions, such as Chronic Fatigue Syndrome (CFS) and Fibromyalgia. Other published research has supported this theory of immune conditioning in the insula, reinforcing the concept of using neural retraining to reduce stimulation in the nervous and immune systems.