First CAR T cell therapy targeting B cell-activating factor receptor eradicates blood cancers

The first CAR T cell therapy targeting the B cell-activating factor receptor on cancerous cells eradicated CD19-targeted therapy-resistant human leukemia and lymphoma cells in animal models, according to City of Hope research published today in Science Translational Medicine. The new therapy will be used in a clinical trial next year for patients who relapsed after CD19 immunotherapy treatments and may […]

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Third of children who need glasses aren’t wearing them

It’s a problem many teachers are familiar with, a student apparently struggling in class, but in fact just suffering from something that’s easily fixed—vision problems—with an inexpensive pair of glasses. It’s estimated that more than 3.4m children aged four to 16 in the UK have been diagnosed with a vision problem. Indeed, vision screenings are carried out routinely in schools […]

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A better MRI marker for disability progression in multiple sclerosis

A retrospective, five-year study of 1,314 patients with multiple sclerosis (MS) has found that atrophied brain lesion volume is the only marker from MRI scans that can accurately predict which patients will progress to the most severe form of the disease. Secondary progressive MS, known as SPMS, typically appears 10 to 20 years after the initial onset and causes patients […]

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New algorithm expands neurologists’ ability to assess for clot-removing procedure

An algorithm developed by faculty at The University of Texas Health Science Center at Houston (UTHealth) can help physicians outside of major stroke treatment centers assess whether a patient suffering from ischemic stroke would benefit from an endovascular procedure to remove a clot blocking an artery. Results of their clinical study using the algorithm were published online today in the […]

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Simple lifestyle modifications key to preventing large percentage of breast cancer cases

Expert reports estimate that one in three breast cancer cases could be prevented by lifestyle modifications. Those modifications include such basics as weight management, physical activity, nutrition, and alcohol consumption, among others. The latest research on risk management and most current lifestyle recommendations will be presented during The North American Menopause Society (NAMS) Annual Meeting in Chicago, September 25-28, 2019. […]

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Breath-holding technique could improve outcomes for radiotherapy patients

A technique that will enable cancer patients to hold their breath during prolonged bouts of radiotherapy treatment has been developed by researchers at the University of Birmingham. In the study, published in Radiotherapy and Oncology, researchers demonstrated that, by safely increasing oxygen levels in the lungs and removing carbon dioxide from blood, it is possible for individuals to hold their […]

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How can more walking be encouraged in cities?

A report investigating travel habits in seven European cities reveals environmental and social drivers that make people choose to walk. The new research reveals these include social factors such as how safe people feel and how concerned they are about air pollution, and urban design, such as how connected streets are and how close people are to public transport links. […]

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CV risk lower with metformin in T2DM and reduced kidney function

(HealthDay)—Treatment with metformin versus sulfonylureas is associated with a reduced risk for major adverse cardiovascular events (MACE) among patients with type 2 diabetes and reduced kidney function, according to a study published online Sept. 19 in the Journal of the American Medical Association to coincide with the annual meeting of the European Association for the Study of Diabetes, held from […]

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