Treatment for: Ulcerative Colitis U.S. Food and Drug Administration Issues Complete Response Letter for Mirikizumab INDIANAPOLIS, April 13, 2023 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) announced the U.S. Food and Drug Administration (FDA) has issued a complete response letter for the mirikizumab biologic license application (BLA) for the treatment of ulcerative colitis (UC). In the letter, the FDA […]

Generic name: tenapanor Treatment for: Hyperphosphatemia of Renal Failure Ardelyx Resubmits New Drug Application to U.S. Food and Drug Administration for Xphozah (tenapanor) WALTHAM, Mass., April 18, 2023 (GLOBE NEWSWIRE) — Ardelyx, Inc. (Nasdaq: ARDX), a biopharmaceutical company founded with a mission to discover, develop and commercialize innovative, first-in-class medicines that meet significant unmet medical needs, today announced the resubmission […]

Cause and mechanismSymptomsGenes and mutationsNADPH complexDiagnosis and treatment ReferencesFurther reading Chronic granulomatous disease (CGD) is a rare genetic immunodeficiency associated with phagocyte function. It was first described in the 1950s. It is caused due to functional impairment in the NADPH (nicotinamide adenine dinucleotide phosphate) oxidase complex and affects 1 in 200,000 live births in the USA. Usually diagnosed at an early […]

The pathogenesis of chronic coughCauses of chronic coughThe diagnosis of chronic coughThe diagnosis of chronic coughReferences Further reading Coughing is a natural defense mechanism that enables secretions produced in the bronchial tract and tree to be cleared to eliminate any inhaled foreign particles that may be physical or biochemical. In addition, it is a common respiratory reaction, or symptom, for diseases […]

Why do some women require a hysterectomy?How are women emotionally affected after a hysterectomy?How to help women with emotional distress after a hysterectomyReferencesFurther reading Hysterectomy is a common surgical procedure that is associated with the removal of the uterus. The uterus or womb is a hollow muscular organ where a fetus grows in pregnant women. Hence, women who undergo a […]

A new study suggests that a common genetic signature may increase a person’s risk of developing substance use disorders, regardless of whether the addiction is to alcohol, tobacco, cannabis or opioids. The research, led by Washington University School of Medicine in St. Louis, eventually could lead to universal therapies to treat multiple substance use disorders and potentially help people diagnosed […]

Revelry mixed with reverence Friday, March 17, as 105 doctors in training at Washington University School of Medicine in St. Louis celebrated Match Day, an annual ritual in which graduating medical students learn where they will train as medical residents. The festivities entailed students opening envelopes unveiling their matches and announcing them to the class during a ceremony at the […]

fezolinetant Treatment for Menopausal Disorders, Hot Flashes Astellas Provides Update on Fezolinetant New Drug Application in U.S. TOKYO, Feb. 19, 2023 /PRNewswire/ — Astellas Pharma Inc. (TSE: 4503, President and CEO: Kenji Yasukawa, Ph.D., “Astellas”) today announced the U.S. Food and Drug Administration (FDA) notified the company that it is extending the original priority review Prescription Drug User Fee Act […]

The brain health of millions of malnourished children stands to benefit following changes to global guidelines for the formulation of ready-to-eat therapeutic food – the standard treatment for severe malnutrition in developing countries. Results of a major clinical trial in Africa led by Mark Manary, MD, professor of pediatrics at Washington University School of Medicine in St. Louis, prompted the […]

What is cyberbullying?The role of social media in cyberbullyingThe mental health of cyberbulliesSimilarities and differences to conventional bullyingPreventing and lessening the psychological harm of cyberbullyingReferences Further reading  Cyberbullying is bullying with the use of electronic devices and is prone to causing mental health issues such as depression and anxiety for both the victim and perpetrator. Cyberbullying can come in many forms, […]