PET imaging shows if PD-1 cancer immunotherapy is working

PD-1 is a protein on our T cells that normally keeps these immune cells from running amok. A growing number of cancer drugs are designed to inhibit PD-1, enabling patients’ T-cells to attack and kill cancerous cells. PD-1 blockers such as pembrolizumab (Keytruda) have been helpful in treating several cancers including melanoma, non-small cell lung cancer, kidney cancer, bladder cancer, […]

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Millions of children exposed to opioid misuse at home, new study reveals

More than 3.8 million U.S. children live with an adult who is inappropriately using opioids, according to a new estimate from the Georgia Institute of Technology’s School of Public Policy. The study, which spans the years 2002 to 2017, also found that while fewer children are living with someone who casually misuses opioids, the number living with adults exhibiting signs […]

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Antibiotics report highlights stewardship, workforce, research needs

The U.S. Centers for Disease Control and Prevention report on the use of antibiotics in health care settings across the United States in 2018 tell us that while progress has been made to promote appropriate use of infection-fighting drugs, strengthened and continued efforts and greater resources are needed to protect some of the most valuable medicines we have and prevent […]

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FDA: approval of zolgensma was based on manipulated data

The maker of Zolgensma (onasemnogene abeparvovec-xioi) gave manipulated data to the U.S. Food and Drug Administration when it approved the drug, the agency said Tuesday. In late May, the FDA approved the gene therapy Zolgensma to treat children with a severe form of spinal muscular atrophy, a leading genetic cause of infant death. The drug costs $2.125 million for a […]

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Is pot safe when pregnant? Study seeks answer, draws critics

Pregnancy started out rough for Leslie Siu. Morning sickness and migraines had her reeling and barely able to function at a demanding New York marketing job, so like rising numbers of U.S. mothers-to-be, she turned to marijuana. “l was finally able to get out from under my work desk,” said Siu, who later started her own pot company and says […]

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NIH establishes network to improve opioid addiction treatment in criminal justice settings

The National Institutes of Health will award 12 grants to form the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder (OUD) in criminal justice settings nationwide. The awards, totaling an estimated $155 million from the National Institute on Drug Abuse, part of NIH, will support the multi-year innovation network, including 10 […]

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Senators unveil compromise to reduce drug costs for seniors

Two senior senators—a Republican and a Democrat—unveiled compromise legislation Tuesday to reduce prescription drug costs for millions of Medicare recipients, while saving money for federal and state health care programs that serve seniors and low-income people. Iowa Republican Charles Grassley and Oregon Democrat Ron Wyden said Tuesday the bill would for the first time limit drug copays for people with […]

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Record drug deaths in Scotland are a national scandal

Every early death, like that of Karen McDade who died in Dundee aged 43, is a tragedy for that person and their family. Sadly, an increasing number of families in Scotland are affected by these tragedies. In 2018, 1,187 people died as a result of drugs. This is a record, up 27% compared with 2018, and in just a decade […]

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Rule requiring drug prices in TV ads blocked by judge

A Trump administration rule to force pharmaceutical companies to disclose the list prices of their drugs in television ads was blocked Monday by a federal judge. The rule, meant to slow rising drug prices, would apply to any drug that costs more than $35 a month and was to take effect this week. Drug makers Merck, Eli Lilly, and Amgen […]

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Are opioids being inappropriately prescribed to treat gout?

Although there are effective treatments for gout, the most common form of inflammatory arthritis, a new Arthritis Care & Research study found that opioids are commonly prescribed to patients with gout who seek treatment at emergency departments. In the study of 456 patients with acute gout discharged from emergency departments in Rhode Island, more than 28% received an opioid prescription. […]

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