FDA: approval of zolgensma was based on manipulated data

The maker of Zolgensma (onasemnogene abeparvovec-xioi) gave manipulated data to the U.S. Food and Drug Administration when it approved the drug, the agency said Tuesday. In late May, the FDA approved the gene therapy Zolgensma to treat children with a severe form of spinal muscular atrophy, a leading genetic cause of infant death. The drug costs $2.125 million for a […]

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Is pot safe when pregnant? Study seeks answer, draws critics

Pregnancy started out rough for Leslie Siu. Morning sickness and migraines had her reeling and barely able to function at a demanding New York marketing job, so like rising numbers of U.S. mothers-to-be, she turned to marijuana. “l was finally able to get out from under my work desk,” said Siu, who later started her own pot company and says […]

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NIH establishes network to improve opioid addiction treatment in criminal justice settings

The National Institutes of Health will award 12 grants to form the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder (OUD) in criminal justice settings nationwide. The awards, totaling an estimated $155 million from the National Institute on Drug Abuse, part of NIH, will support the multi-year innovation network, including 10 […]

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Senators unveil compromise to reduce drug costs for seniors

Two senior senators—a Republican and a Democrat—unveiled compromise legislation Tuesday to reduce prescription drug costs for millions of Medicare recipients, while saving money for federal and state health care programs that serve seniors and low-income people. Iowa Republican Charles Grassley and Oregon Democrat Ron Wyden said Tuesday the bill would for the first time limit drug copays for people with […]

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Record drug deaths in Scotland are a national scandal

Every early death, like that of Karen McDade who died in Dundee aged 43, is a tragedy for that person and their family. Sadly, an increasing number of families in Scotland are affected by these tragedies. In 2018, 1,187 people died as a result of drugs. This is a record, up 27% compared with 2018, and in just a decade […]

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Rule requiring drug prices in TV ads blocked by judge

A Trump administration rule to force pharmaceutical companies to disclose the list prices of their drugs in television ads was blocked Monday by a federal judge. The rule, meant to slow rising drug prices, would apply to any drug that costs more than $35 a month and was to take effect this week. Drug makers Merck, Eli Lilly, and Amgen […]

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Are opioids being inappropriately prescribed to treat gout?

Although there are effective treatments for gout, the most common form of inflammatory arthritis, a new Arthritis Care & Research study found that opioids are commonly prescribed to patients with gout who seek treatment at emergency departments. In the study of 456 patients with acute gout discharged from emergency departments in Rhode Island, more than 28% received an opioid prescription. […]

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Patients missing out on arthritis drugs, shows study

A class of drugs that has been successfully treating patients with severe rheumatoid arthritis should be made available for moderate suffers, too, University of Manchester scientists say. A study led by Dr. James Gwinnutt reveals that some rheumatoid arthritis patients who do not qualify for biological treatments on the NHS have high levels of disability caused by the condition. It […]

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Opioid crisis burning out doctors, study finds

As the opioid crisis take a deadly toll in human lives, the complex needs of patients in chronic pain are also leaving their doctors increasingly exhausted and overwhelmed, a new Western-led study says. In their detailed interviews and clinic observations, researchers found many primary-care physicians are close to burnout in caring for patients in pain. “You are in between a […]

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New drug mimics benefits of ketamine for depression

A new small-molecule drug produced a rapid antidepressant response similar to that of ketamine when tested in mice, a new Yale-led study published April 16 in the Journal of Clinical Investigation shows. The effects of the drug, called NV-5138, in rodent models mimicked the rapid actions of the anesthetic ketamine, a variation of which, Esketamine, was recently approved by the […]

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