Using artificial intelligence to deliver personalized radiation therapy

New Cleveland Clinic-led research shows that artificial intelligence (AI) can use medical scans and health records to personalize the dose of radiation therapy used to treat cancer patients. Published today in The Lancet Digital Health, the research team developed an AI framework based on patient computerized tomography (CT) scans and electronic health records. This new AI framework is the first […]

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High BMI, weight gain linked to lasting decrease in ALS risk

(HealthDay)—High body mass index (BMI) and weight gain are associated with a reduced long-term risk for amyotrophic lateral sclerosis (ALS), according to a study published online June 26 in Neurology. Ola Nakken, M.D., from the University of Oslo in Norway, and colleagues collected objectively measured BMI from 85 percent of all citizens aged 20 to 70 years living in 18 […]

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Interdisciplinary approach decreases broad spectrum antibiotic usage

An interdisciplinary approach to antimicrobial stewardship involving comprehensive blood culture identification (BCID) testing decreased broad spectrum antibiotic use, according to new research presented last week in Philadelphia at the 46th Annual Conference of the Association for Professionals in Infection Control and Epidemiology (APIC). The microbiology lab at Einstein Medical Center Montgomery in Pennsylvania, in collaboration with the antimicrobial stewardship team, […]

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Long-term statin use associated with lower glaucoma risk

A new study brings the connection between statin use and risk of glaucoma into sharper focus. Investigators from Brigham and Women’s Hospital have found that using statins for five or more years is associated with lower risk of primary open-angle glaucoma. Results of the study were published recently in JAMA Ophthalmology. Glaucoma, a leading cause of blindness, is a condition […]

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New combination therapy established as safe and effective for prostate cancer

A novel therapy using two targeted treatments for prostate cancer has been shown to maximize efficacy while reducing side effects according to research presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2019 Annual Meeting. Prostate cancer is the most commonly diagnosed cancer among men in the United States, other than skin cancer. According to the American Cancer […]

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Embryonic microRNA fuels heart cell regeneration, researchers show

By adulthood, the heart is no longer able to replenish injured or diseased cells. As a result, heart disease or an event like a heart attack can be disastrous, leading to massive cell death and permanent declines in function. A new study by scientists at the Lewis Katz School of Medicine at Temple University (LKSOM), however, shows that it may […]

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Cancer control: Structure of important transport protein solved

For the first time, Bernese researchers have been able to solve the structure of a transport protein and thus to describe the functional mechanism that plays a significant role in the survival of cancer cells. This is an important step towards developing effective inhibitors to fight tumor growth. Certain cancer cells depend on exporting the metabolite lactate, which accumulates during […]

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Treatment for common cause of diarrhea more promising

One of the most common causes of diarrhea worldwide – accounting for millions of cases and tens of thousands of deaths, mostly of small children – is the parasite Cryptosporidium. Doctors can treat children with Cryptosporidium for dehydration, but unlike many other causes of diarrhea, there are no drugs to kill the parasite or vaccines to prevent infection. Now, researchers […]

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How hepatitis B and delta viruses establish infection of liver cells

Princeton University researchers have developed a new, scalable cell culture system that allows for detailed investigation of how host cells respond to infection with hepatitis B (HBV) and delta virus (HDV). The paper describing their findings was published online on June 18, 2019 in the journal Hepatology. HBV causes an acute illness that is usually rapidly cleared by adults with […]

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Detecting pressure ulcers in sweat and sebum

Pressure ulcers are a major burden to patients, carers and the healthcare system. Particularly vulnerable populations are elderly, bedridden and spinal cord injured individuals. Ph.D. researcher Jibbe Soetens investigated the response of the human skin to prolonged loading. Hospitals can use his results to detect and even predict pressure ulcers. Also the design of, for example, mattresses and wheelchairs can […]

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